When engaging in NFL over/under betting, it's crucial to analyze team statistics, recent performance, and weather conditions. Look for trends in scoring, such as how often teams hit the over or under in past games. Pay attention to injuries, as key player absences can significantly impact scoring potential. Additionally, consider the matchup; high-powered offenses against weak defenses often lead to higher totals. Lastly, shop around for the best lines, as different sportsbooks may offer varying totals, maximizing your potential for profit.